Search on: SYK KINASE 
Descriptors Found: 1
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Descriptor English:   Syk Kinase 
Descriptor Spanish:   Quinasa Syk 
Descriptor Portuguese:   Quinase Syk 
Synonyms English:   SYK Tyrosine Kinase
Spleen Tyrosine Kinase
Kinase, SYK Tyrosine
Kinase, Spleen Tyrosine
Kinase, Syk
Tyrosine Kinase, SYK
Tyrosine Kinase, Spleen  
Tree Number:   D08.811.913.696.620.682.725.650
D12.644.360.900
D12.776.476.913
Definition English:   An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development. 
See Related English:   src Homology Domains
 
History Note English:   2017 (1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56517 
Unique Identifier:   D000072377 

Occurrence in VHL: 		 

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